Events are being held to mark the 20th World Aids Day, many highlighting the need to fight continued prejudices against people with HIV-Aids.
The UN recently reduced its estimate of the number of people with HIV/Aids, but the figure still stands at 33 million.
UN chief Ban Ki-moon said strong leadership was needed if the fight against the disease was to be won.
Campaigners have warned that progress in treating and slowing the disease is breeding complacency about the risks.
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